Effects of a Brief Mental Exercise on Emotional Processing
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首次提交日期 ICMJE | October 4, 2018 | ||
首次发布日期e ICMJE | October 5, 2018 | ||
最后更新发布日期 | October 5, 2018 | ||
预计研究开始日期 ICMJE | May 24, 2017 | ||
预计主要完成日期 | October 2018 (主要结果测量的最终数据收集日期) | ||
目前主要观察指标 ICMJE |
Performance in a facial expression recognition task[ Time Frame: Completed at day 8 after exercise has been started ] Participants are presented with individual pictures of facial expressions of emotions. Each presented face displays one of six basic emotions (anger, disgust, fear, happiness, sadness, or surprise). Each emotional expression is presented at different levels of intensity which have been created by combining shape and texture features of the two extremes "neutral" (0%) and "full prototypical emotion" (100%) to varying degrees. Examples of neutral facial expressions are presented as well. Participants are instructed to correctly classify each facial expression as angry, disgusted, fearful, happy, sad, surprised or neutral both as quickly and as accurately as possible. Responses are made by pushing one out of seven labelled keys on a response box. Hit rates, false alarm rates, and reaction times for correct classifications are measured separately for each emotion. |
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原始主要观察测量 ICMJE | 与当前相同 | ||
目前的二级观察 ICMJE |
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描述性信息 | |||
简略标题 ICMJE | Effects of a Brief Mental Exercise on Emotional Processing | ||
正式标题 ICMJE | Can Brief Daily Mental Exercises Change the Way the Human Brain Processes Certain Kinds of Information? | ||
简要概况 | The aim of this study is to explore whether a brief mental exercise (developed and widely advocated in the field of positive psychology) can change the processing of emotion-related information in a similar way as previously observed for antidepressant drugs. Healthy volunteers are randomly allocated to a 7-day practice of the "Three Good Things" (TGT) exercise or a previously used placebo exercise (unspecified childhood memory recall) with study participants as well as investigators being blind as to which practice is conducted. After a 7-day practice period, all study participants undergo testing with the Oxford Emotional Test Battery, an established battery of cognitive tasks that allow to assess how emotional information is processed. We hypothesise that the TGT exercise, as compared to the placebo exercise, can push the processing of emotional information towards a prioritisation of positive (relative to negative) input. |
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详细说明 | Background and objective: Previous research indicates that various physiological treatments for depression (especially antidepressant drugs) can induce positive biases in emotional information processing and it has been suggested that this might be a crucial common mechanism through which they exert their clinical effects. In this study we aim to investigate whether similar positive biases can also be induced by a brief mental exercise (developed and widely used within the field of positive psychology) that has previously been shown to have antidepressant and/or happiness-enhancing effects. Methods: Using a double-blind, parallel-group design, 100 healthy volunteers (male and female) are randomly allocated to a 7-day mental exercise practice conducting either the widely reported Three Good Things (TGT) exercise or a previously established placebo condition (unspecific childhood memory recall). After 7 days of practice, all participants undergo testing with the Oxford Emotional Test Battery in order to assess emotional information processing in different cognitive domains. This battery consists of a facial expression recognition task, an emotional categorization task, an emotional dot probe task, an emotional recall task and an emotional recognition task. In addition, prior to and immediately after the 7-day practice period salivary cortisol awakening response and subjective state (using various questionnaires) is assessed. Hypotheses: Our working hypothesis is that, similar to physiological antidepressant interventions, the TGT exercise (as compared to the placebo exercise) might induce biases towards positive stimuli in multiple cognitive domains. Implications of the study: This study will show whether engaging in a simple mental exercise can alter emotional information processing in a similar way as previously observed for antidepressant drugs and other physiological interventions. | ||
研究类型 ICMJE | Interventional | ||
研究阶段 | N/A | ||
研究设计 ICMJE | 分配: Randomized 干预模型: Parallel Assignment 干预模型描述: 盲法: Interventional 盲法描述: 主要目的: Basic Science |
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适用条件 ICMJE | |||
干预项目 ICMJE |
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研究工具 |
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招募状态 ICMJE | Recruiting | ||
预计入组 ICMJE |
100 | ||
原始预计入组 ICMJE | 与当前相同 | ||
预计研究完成日期 | October 2018 | ||
预计主要完成日期 | October 2018 (主要结果测量的最终数据收集日期) | ||
合格标准 ICMJE | Inclusion Criteria: 1. Female or male 2. Age: 18 to 65 years 3. Good general health 4. Competency to give informed consent Exclusion Criteria: 1. Any current or past psychiatric disorder 2. Any first-degree relative with a diagnosis of schizophrenia-spectrum or other psychotic disorder, bipolar disorder, or depressive disorder 3. Regular engagement in mental exercises specifically aimed at improving cognitive abilities (concentration, attention, memory etc.), mood, or general well-being, such as (online) cognitive training, positive psychology exercises, regular meditation or mindfulness practices, yoga practices, or psychotherapeutic exercises. 4. Regular engagement in any of the exercises outlined above within the last 6 months. 5. Any severe medical condition not stabilized at the time of the study (e.g. asthma, heart disease, epilepsy) 6. Any current or past physical illness that has the potential to significantly affect mental functioning (e.g. stroke, Parkinson's disease, multiple sclerosis) 7. Current intake of medication that has a significant potential to affect mental functioning, or intake of such medication in the previous 3 months (e.g. antidepressants, neuroleptics, tranquilizers) 8. Any intake of recreational drugs in the last 3 months before the experiment 9. Regular consumption of higher doses of alcohol (more than 2 pints of beer or equivalent on more than 3 days a week within the last month) 10. Any other reasons that preclude participants from full participation in the experiment (e.g. insufficient knowledge of English language) 11. Any other condition which can make participation in the study harmful for a participant, or which can severely compromise the quality of the data (e.g. low intellectual functioning) | ||
性别 |
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年龄 | 最小年龄:18 Years ,最大年龄:65 Years | ||
接受健康的志愿者 | 没有 | ||
可入组国家 ICMJE | United Kingdom | ||
管理信息 | 数据检测委员会 | No | |
研究涉及美国FDA监管的产品 |
研究美国FDA监管的药品: No 研究涉及美国FDA监管的设备产品: No |
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IPD 共享声明 |
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责任方 | , | ||
研究赞助商 ICMJE | University of Oxford | ||
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验证日期 | September 2018 | ||
ICMJE 国际医学期刊编辑委员会和 世界卫生组织 ICTRP 要求的元素 |